Professor Wong Hin Seng

Professor Wong Hin Seng

  • Clinical Professor in Medicine and Nephrology
Department of Clinical Medicine and Surgery
  • Sir Jeffrey Cheah 红杏视频 Medical School
Faculty of Medical and Life Sciences

Biography

Professor Dr Wong Hin Seng is a Clinical Professor in Medicine and Nephrology at the School of Medical & Life Sciences, 红杏视频 University, and a Consultant Nephrologist at 红杏视频 Medical Centre. He obtained his Doctor of Medicine (MD) and Master in Medicine (Internal Medicine) from Universiti Kebangsaan Malaysia and completed his nephrology fellowship at the Sheffield Kidney Institute, England, in 1997.

Professor Dr Wong is currently serving as a councillor of the Asian Pacific Society of Dialysis Access. He has previously held leadership roles as the past president of the Malaysian Society of Nephrology, the Malaysian Society of Diagnostic & Interventional Nephrology, and the Post Graduate Renal Society of Malaysia. He is a fellow of several prestigious institutions, including the Royal College of Physicians of Edinburgh, the International Society of Nephrology, the Academy of Medicine of Malaysia, the College of Physicians Malaysia, and the Malaysian Society of Nephrology.

With over 80 publications in peer-reviewed journals, Professor Dr Wong has also authored more than 30 reports and book chapters. He has delivered over 190 lectures at scientific meetings, both locally and internationally, and presented more than 250 research papers at conferences around the world.

Academic & Professional Qualifications

  • Master in Medicine (Internal Medicine), Universiti Kebangsaan Malaysia (1994)
  • MD, Universiti Kebangsaan Malaysia (1988)
  • MRCP(UK) diploma (1997)
  • Fellow of the Royal College of Physicians of Edinburgh [FRCP(Edin)
  • Fellow of the International Society of Nephrology (FISN)
  • Fellow of the Academy of Medicine Malaysia (FAMM)
  • Fellow of the College of Physicians Malaysia (FCoPM(Nephrology)

Research Interests

  • Kidney Transplantation
  • Interventional Nephrology
  • Chronic Kidney Disease
  • Glomerulonephritis

Teaching Areas

  • Internal Medicine
  • General Nephrology
  • Kidney Transplantation
  • Interventional Nephrology

Courses Taught

  • Good Clinical Practice

Notable Publications

1.    Effect of CYP3A5*3, ABCC2-24T, and ABCC2 C3972T genetic polymorphisms on direct cost of kidney transplant recipients. Choong C, Islahudin F, Makmor-Bakry M, Tahir N, Wong H-S, Yahya R. Cureus 16(9):e69221.doi:10.7759/cureus.69221 


2.    The impact of ABCC2-24C>T gene polymorphism on graft survival in kidney transplant recipients. Chiau Ling Choong, Farida Islahudin, Hin-Seng Wong, Rosnawati Yahya, Nor Asyikin Mohd Tahir, Mohd Makmor-Bakry. J Personalized Med 2024;14:440. https://doi.org/10.3390/jpm14040440  


3.    Precision medicine in erythropoietin deficiency and treatment resistance: A novel approach to management of anaemia in chronic kidney disease. Nava Yugavathy, Bashar Mudhaffar Abdullah, Soo Kun Lim, Abdul Halim Bin Abdul Gafor, Muh Geot Wong, Sunita Bavanandan, Hin-Seng Wong, Hasniza Zaman Huri. Curr Issues Mol. Biol. 2023;45:6550-6563


4.    COVID-19 Death and Kidney Disease in a Multiracial Asian Country. Bak Leong Goh, Malini Shanmuganathan, Kalaiarasu Peariasamy, Nor Arisah Misnan, Suresh Kumar Chidambaram, Eddie Fook Sem Wong, Mohan Dass Pathmanathan, Kim Liong Ang, Hin Seng Wong, Lena Lay Ling Yeap. Nephrology 2022; 27(7): 566-576


5.    Comparison of clinical outcomes among deceased donor kidney transplant recipients before and after utilizing estimated posttransplant survival score for kidneys allocation in Malaysia. Yong-Muh Ng, Yik-Shen Lim, Lik-Wee Ee, Voon-Ken Fong, Chun-Leong Low, Mohamad Zaimi Abdul Wahab, Hin-Seng Wong, Rosnawati Yahya. Transplant Proc 2022;54(2):278-281


6.    Predictive factors, treatment, and outcomes of coagulase-negative staphylococcal peritonitis in Malaysian peritoneal dialysis patients: A single-center study. Siew Yan Lau; Boon Cheak Bee; Hin-Seng Wong; Marhanis Salihah Omar; Bahari, Norazlah.鈥塈nternational Journal of Nephrology Volume 2022, Article ID 8985178


7.    Adverse drug reactions of antihypertensives and Cyp3A5*3 polymorphism among chronic kidney disease patients. Fei Yee Lee, Farida Islahudin, Adbul Halim Abdul Gafor, Hin-Seng Wong, Sunita Bavanandan, Shamin Mohd Saffian, Adyani Md Redzuan, Mohd Makmor-Bakry. Front. Pharmacol 2022; 13: Art 848808


8.    Muscle status response to oral nutritional supplementation in HD pats with protein energy wasting: A multicentre randomized, open label controlled trial. S Sahathevan, T Karupaiah, BH Khor, BKS Singh, ZAM Daud, E Fiaccadori, A Sabatino, K Chinna, AHA Gafor, S Bavananthan, R Yahya, Z Wahab, BL Goh, Z Morad, BC Bee, HS Wong. Frontier in Nutritions 2021;8:Art 743324 

 
9.    Everolimus-facilitated calcineurin inhibitor reduction in Asian de novo kidney transplant recipients: Two-year results from the subgroup analysis of the TRANSFORM study. Y Watarai, R Danguilan, C Casasola, SS Chang, P Ruangkanchanasetr, T Kee, HS Wong, T Kenmochi, AJ Amante, KH Shu, A Ingsathit, P Bernhardt, MP Hernandez-Gutierrez, DJ Han, MS Kim. Clinical Transplantation 2021;35:e14415


10.    Factors associated with the frequency of antihypertensive drug adjustments in chronic kidney disease patients: a multicentre, 2 year retrospective study. Fei Yee Lee, Farida Islahudin, Mohd Makmor Bakry, Hin Seng Wong, Sunita Bavanandan. International Journal of Clinical Pharmacy 202143 : 1311-1321


11.    Clinical effectiveness of a Malaysian-manufactured CAPD product: A randomised trial. Wen Yao Mak, Chin Tho Leong, Loke Meng Ong, Sunita Bavanandan, Lily Mushahar, Bak Leong Goh, Hin Seng Wong et al. Peritoneal Dialysis International 2021;41(3):273-283


12.    Effects of CYP3A5 Polymorphism on Rapid Progression of Chronic Kidney Disease: A Prospective, Multicentre Study. Fei Yee Lee, Farida Islahudin, Aina Yazrin Ali Nasiruddin, Abdul Halim Abdul Gafor, Hin鈥怱eng Wong et al. Journal of Personalized Medicine 2021, 11, 252


13.    Hepatic Adverse Drug Reactions in Malaysia: An 18-Year Review of the National Centralized Reporting System. Lee Fei Yee, Hin-Seng Wong, Huan-Keat Chan, Norleen Mohamed Ali, Muhammad Radzi Abu Hassan, Haniza Omar, Noor Aliza binti Abd Mutalib. Pharmacoepidemiology & Drug Safety, 2020;29:1669-1679


14.    Clinical and genetic markers of erythropoietin deficiency anaemia in chronic kidney disease (pre-dialysis) patients. Nava Nava Yugavathy, Hasniza Zaman Huri, Lim Soo Kun, Abdul Halim Abdul Gafor, Wong Muh Geot, Sunita Bavanandan, Hin-Seng Wong. Biomarkers in Medicine 2020;14(12):1099-1108


15.    Survival advantage of initiating dialysis in elderly and non elderly incident ESRD patients. Chin C. Ch鈥檔g, Loke M. Ong, Kelvin K.M. Beh, Wan S. Md Yusuf, Thian F. Chew, Lai S. Hooi, Hin-Seng Wong, Shahnaz Shah Firdaus Khan, Ghazali Ahmad. Nephrology 2020;25(8): 644-651  

 
16.    Effectiveness of drug allergy card to prevent repeated prescribing of allergenic medications in a Malaysian public hospital. Fei Yee Lee, Huan Keat Chan, Hin Seng Wong. Pharmacoepidemiology & Drug Safety, 2019; 28(5):760-761  


17.    Hepatitis Screening and Treatment Campaign in Malaysia-Validation of Low-cost Point of Care Screening Tests and Nucleic Acid Tests for Hepatitis B and C. Muhammad Radzi AH, Soek S Tan, Rosmawati Mohamed, Fauziah Jaya, Senamjit K, Azlida C Aun, Ghazali A Kutty, Hin S Wong, Rafidah Abdullah, Mohd R Seman, Mamun Al Mahtab, Zaki Morad, Teck-Onn Lim. Euroasian Journal of Hepato-Gastroenterology, 2018; 8(2):101-107


18.    Dose-Response Relationship Between Diltiazem and Tacrolimus and Its Safety in Renal Transplant Recipients. C.L. Choong, H.S. Wong, F.Y. Lee, C.K. Lee, J.V. Kho, Y.X. Lai, T. Vikneswarana. Transplantation Proceedings, 2018;50(8):2515-2520


19.    The Cost and Utility of Renal Transplantation in Malaysia. Sunita Bavanandan, Yok-Chin Yap, Ghazali Ahmad, Hin-Seng Wong, Soraya Azmi, Adrian Goh. Transplantation Direct 2015; 1(10):e45


20.    Pharmacogenotyping of CYP3A5 in predicting dose adjusted trough levels of tacrolimus among Malaysian kidney transplant patients. Hamzah S, Teh LK, Siew JS, Ahmad G, Wong HS, Zakaria ZA, Salleh. Can J Physiol Pharmacol 2014; 92(1):50-57


21.    Ratio of capacitance/BMI reflects deficit in nutritional concentration while CH2 reflects total nutritional deficit in CAPD and general population. Keng-Hee Koh & Hin-Seng Wong. Open J Nephrol 2013,3:194-203


22.    Conversion to enteric coated Mycophenolate Sodium from Mycophenolate Mofetil in stable renal transplant patients: Results of an Asia Pacific study. Lee PH, Vathsala A, Han DJ, Chan TM, Wong HS, Woodcock C, Kurstjens. Nephrology 2013;18:57-62  


23.    Normalized bioimpedance indices are better predictors of outcome in peritoneal dialysis patients. Koh KH, Wong HS, Go KW, Morad. Perit Dial Int 2011;31:574-582


24.    A randomised, multi-centre, open label trial to determine peritonitis rate, product defect and technique survival between ANDY-Disc庐 and Ultrabag庐 in patients on CAPD. Hin-Seng Wong, Loke-Meng Ong, Teck-Onn Lim, et al.  American Journal Kidney Disease 2006; 48(3): 464-472


25.    Randomised controlled trial of pulse intravenous cyclophosphamide versus MMF in the induction therapy of proliferative lupus nephritis. Loke Meng Ong, Lai Seong Hooi, Teck Onn Lim, Bak Leong Goh, Ghazali Ahmad, Rozina Ghazalli, Sue Mei Teo, Hin Seng Wong, Si Yen Tan, Wan Shaariah, Chwee Choon Tan, Zaki Morad. Nephrology 2005; 10(5):504-510


26.    Prevention of renal failure: The Malaysian experience. Lai Seong Hooi, Hin Seng Wong, Zaki Morad. Kidney International 2005; 67(supp 94):pp S1-S5


27.    Economic Evaluation of Centre Haemodialysis and Continuous Ambulatory Peritoneal Dialysis in Ministry of Health Hospitals, Malaysia. Lai Seong Hooi, Teck Onn Lim, Adrian Goh, Hin Seng Wong, Chwee Choon Tan, Ghazali Ahmad, Zaki Morad. Nephrology 2005; 10 (1):25-32. 


28.    A Randomised, Multi-center, Open label trial to establish the therapeutic equivalence between Carex庐 and Ultra庐 in patients on CAPD. Loke-Meng Ong, Teck-Onn Lim, Lai-Seong Hooi, Zaki Morad, Poh-Choo Tan, Hin-Seng Wong, et al. Peritoneal Dialysis International 2003; 23 (Suppl 2) : S139-S143.


29.    Outcome assessment of the Ministry of Health dialysis programme. Lim TO, Lim YN, Wong HS, Zaki M. et al. Med J Malaysia 1999; 54: 459-470


30.    Cost Effectiveness evaluation of the Ministry of Health dialysis programme. Lim TO, Lim YN, Wong HS, Zaki M. et al. Med J Malaysia 1999;54: 442-452
 

Professional Associations

1.    Councillor & Congress Chair (2018-2025) of the Asian Pacific Society of Dialysis Access (APSDA)
2.    Past president (2010-2012) & Fellow of the Malaysian Society Nephrology (MSN)
3.    Past president (2016-2024) & founding member of the Malaysian Society of Diagnostic & Interventional Nephrology (MSDIN)
4.    Past president (2016-2018) of the Post Graduate Renal Society of Malaysia (PGRSM)
5.    Past chairman of Malaysian Organ Sharing System (eMOSS) committee (2002-2018)
6.    Past chief editor of Malaysian Dialysis and Transplant Registry (2016-2018)
7.    Member of the Advisory Board of National Renal Registry (2001-2019)
8.    Member of the Advisory Board of Malaysian Registry of Renal Biopsy (2007-2021)
9.    Fellow of the Royal College of Physicians of Edinburgh [FRCP(Edin)]
10.    Fellow of the International Society of Nephrology (FISN)
11.    Fellow of the Academy of Medicine Malaysia (FAMM)
12.    Fellow of the College of Physicians Malaysia [FCoPM(Nephrology)]