Professor Teoh Kean Hooi

Professor Teoh Kean Hooi

  • Clinical Professor in Pathology
Department of Clinical Medicine and Surgery
  • Sir Jeffrey Cheah Ƶ Medical School
Faculty of Medical and Life Sciences

Biography

Dr Teoh graduated with a medical degree in 1999 from the Royal College of Surgeons in Ireland and completed his postgraduate training in 2009, earning a Master’s in Pathology from the University of Malaya. He initially worked at Penang General Hospital under the Malaysian Ministry of Health before joining the University of Malaya as a senior lecturer. Dr Teoh was promoted to Associate Professor in 2017 and briefly served as the Head of the Department of Pathology at University of Malaya / University Malaya Medical Center, prior to transitioning to private practice at Ƶ Medical Centre.

Dr Teoh also served as a Consultant Pathologist at University Malaya Specialist Centre, specializing in diagnostic surgical pathology and cytopathology. Additionally, he worked as a pathologist at Genomic Medical Science @ UM (GEMS@UM), a laboratory focused on diagnostic molecular pathology in surgical and cytopathological samples.

With a strong interest in clinical research, Dr Teoh has been involved in various clinical trials and has published over 30 peer-reviewed papers in fields including breast, gastrointestinal, and female genital tract pathology. His current research focus is primarily in breast pathology. He was part of the committee that developed the consensus guidelines on Human Epidermal Growth Factor Receptor 2 (HER2)-low testing in breast cancer in Malaysia (2024) and served as a member of the technical working group responsible for updating the technical requirements in Cytopathology for laboratory accreditation under Standards Malaysia.

Dr Teoh has also held leadership roles within the professional community, including serving as the past treasurer of the College of Pathologists, Academy of Medicine of Malaysia. He has been actively involved as an examiner and coordinator for the Conjoint Master in Pathology (Anatomical Pathology) programs and was a member of the Conjoint Board for Pathology. He also contributed to the development of the Pathology National Post-Graduate Program.

Academic & Professional Qualifications

  • MPath, University of Malaya, Malaysia (2009)
  • MBChB, BAO, LRCP & LRSI, Royal College of Surgeons, Ireland (1999)

Research Interests

  • Surgical Pathology
  • Breast Pathology

Teaching Areas

  • General Pathology
  • Surgical Pathology
  • Cytopathology

Notable Publications

  1. Nur Diyana Md Nasir, Cedric Chuan Young Ng, Vikneswari Rajasegaran, Suet Far Wong, Wei Liu, Gwendolene Xin Pei Ng, Jing Yi Lee, Peiyong Guan , Jing Quan Lim, Aye Aye Thike, Valerie Cui Yun Koh, Benjamin Nathanael Loke, Kenneth Tou En Chang, Mihir Ananta Gudi, Derrick Wen Quan Lian, Preetha Madhukumar, Benita Kiat Tee Tan, Veronique Kiak Mien Tan, Chow Yin Wong, Wei Sean Yong, Gay Hui Ho4, Kong Wee Ong, International Fibroepithelial Consortium†, Patrick Tan, Bin Tean Teh and Puay Hoon Tan. †International Fibroepithelial Consortium: Norraha Abd Rahman, SM Khodeza Nahar Begum, Phaik Leng Cheah, Chih Jung Chen, Emmanuel Dela Fuente, Aaron Han, Oi Harada, Naoki Kanomata, Cheok Soon Lee, Jonathan Yu Han Lee, Mohammed Kamal, Rieko Nishimura, Yasuyo Ohi, Elinor J Sawyer, Kean Hooi Teoh, Alex Koon Ho Tsang, Julia Yuen-Shan Tsang, Gary MK Tse, Rin Yamaguchi,Kurume. Genomic characterisation of breast fibroepithelial lesions in an international cohort. Journal of Pathology 2019; Volume 249, Issue 4: 447-460.
  2. Kong, Yek-Ching; Bhoo-Pathy, Nirmala; O’Rorke, Michael; Subramaniam, Shridevi; Bhoo-Pathy, Nanthini; See, Mee-Hoong; Jamaris, Suniza; Teoh, Kean-Hooi; Bustam, Anita Z.; Looi, Lai-Meng; Taib, Nur Aishah; Yip, Cheng-Har. The association between methods of biopsy and survival following breast cancer. A hospital registry based cohort study. Medicine 99[6]: e19093, February 2020.
  3. Anthony Rhodes, Kean-Hooi Teoh, Mee-Hoong See, Kumar Ganesan, Lai-Meng Looi. Breast Cancer Hormone Receptor Testing in Asia: Is It Time to Think Again on Expected Positivity Rates and Methods of Scoring? Pathology, Volume 52, Issue 3 (April 2020). PMID: 32107079: 10.1016/j.pathol.2019.12.006.
  4. Po-Lian Kong , Phaik-Leng Cheah, Kein-Seong Mun, Seow-Fan Chiew, Tze-Pheng Lau, Cing-Chai Koh, Kean-Hooi Teoh, Abdul Rahman Nazarina anLai-Meng Looi. FISHing for 1p19q codel in oligodendroglioma. Malays J Pathol 2020; 42(3): 369 – 376.
  5. Fadzli F, Rahmat K, Ramli MT, Rozalli FI, Hooi TK, Fadzli AN, Hoong SM, Ramli NM, Taib NA. Spectrum of imaging findings of papillary breast disease: a radiopathological review in a tertiary center. Medicine. 2021;100:16(e25297).
  6. Md Pauzi SH, Masir N, Yahaya A, Mohammed F, Tizen Laim NM, Mustangin M, Aizudin AN, Talib A, Teoh KH, Karim N, Oy-Leng JW, Rajadurai P. HER2 testing by immunohistochemistry in breast cancer: A multicenter proficiency ring study. Indian J Pathol Microbiol 2021;64:677-82.
  7. Ng CC, Nasir ND, Loke BN, Tay TK, Thike AA, Rajasegaran V, Liu W, Lee JY, Guan P, Lim AH, Chang KT, International Fibroepithelial Consortium. Genetic differences between benign phyllodes tumors and fibroadenomas revealed through targeted next generation sequencing. Modern Pathology. 2021 Jul 1;34(7):1320-32.
  8. Afiqah Abu Samah, Mohammad Faizal Ahmad Fauzi, See Yee Khor, Jenny Tung Hiong Lee, Kean Hooi Teoh, Lai Meng Looi, Sarina Mansor. Mitotic cells detection in H&E-stained breast carcinoma images. International Journal of Biomedical Engineering and Technology Vol. 40, No. 1.
  9. Seow-Fan Chiew, Lai-Meng Looi , Phaik-Leng Cheah , Kean-Hooi Teoh , Siow-Wee Chang, Siti-Fairus Abdul Sani. Epithelial-mesenchymal transition profiles in triple negative breast carcinoma may explain its aggressive nature. Malays J Pathol 2023; 45(3): 363 – 374.
  10. Rajadurai, P.; Ravindran, S.; Lee, B.R.; Md Pauzi, S.H.; Chiew, S.F.; Teoh, K.H.; S. Raja Gopal, N.; Md Yusof, M.; Yip, C.H. Consensus Guidelines on Human Epidermal Growth Factor Receptor 2 (HER2)‐Low Testing in Breast Cancer in Malaysia. Cancers 2024, 16, 2325.

 

Professional Associations

  1. Member, International Academy of Cytology, Germany (2014)
  2. Member, Academy of Medicine Malaysia, Malaysia (2014)
  3. Member, past Treasurer (2016-2017), College of Pathologist, Malaysia (2014)