Professor Ho Weang Kee

Professor Ho Weang Kee

  • Professor
Department of Biomedical Sciences
  • Sir Jeffrey Cheah ºìÐÓÊÓÆµ Medical School
Faculty of Medical and Life Sciences
SDGs Focus

Biography

Dr Weang-Kee Ho is a Professor of Health Data Science at the Faculty of Medical and Life Sciences, ºìÐÓÊÓÆµ University, and a Visiting Scientist at Cancer Research Malaysia. Her research focuses on identifying the genetic and lifestyle determinants of non-communicable diseases. Funded by the Wellcome Trust and the MRC-ASM Newton-Ungku Omar Fund, Dr Ho’s team builds breast cancer risk assessment tools for multi-ethnic Asian populations, integrating lifestyle factors, genetic information, and mammogram images. Additionally, supported by the Basser External Research Grant Program, Dr Ho’s team conducts research on the identification of lifestyle and genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers of Asian ancestry. Collaborating with academic and industry partners, the team also conducts studies to determine women’s health screening behaviour and cost-effective screening strategies in the context of low- and middle-income countries. Dr Ho is a statistician by training and has been awarded the Loreal-UNESCO for Women in Science National Fellowship in 2018, the Loreal-UNESCO International Rising Talent award in 2019, and the Wellcome Trust Career Development Award in 2023.

Academic & Professional Qualifications

  • PhD in Mathematics, University of Newcastle (UK), (2010)
  • BSc (Hons) Mathematics, Northumbria Univeristy (UK), (2005)

Research Interests

  • Precision Health and Risk Stratification
  • Health Data Science
  • Cancer Genetic Epidemiology
  • Statistical Genetics
  • Polygenic/Trans-ancestry risk prediction
  • Multi-Modal Modelling
  • Evaluation of risk-based screening strategies

Teaching Areas

  • Statistics
  • Biostatistics
  • Risk Prediction Modelling

Courses Taught

  • Statistical Methods and Models
  • Applied Statistical Modelling

Notable Publications

  1. Tai, M.C., ... Teo, S.H., Ho, W.K. 2025 Polygenic risk score for breast cancer risk prediction in Asian BRCA1 and BRCA2 pathogenic variants carriers. NPJ breast cancer
  2. Ang, B.H., Teo, S.H., Ho, W.K., et. al 2025 Systematic review and meta-analysis of lifestyle and reproductive factors associated with risk of breast cancer in Asian women. CEBP.
  3. Ho, W.K., et. al 2024 Age-specific breast and ovarian cancer risks associated with germline BRCA1 or BRCA2 pathogenic variants - an Asian study of 572 families. The Lancet Regional Health - Western Pacific.
  4. Ho, W.K., Tai, M.C., et. al 2022 Polygenic risk scores for prediction of breast cancer risk in Asian populations. Genetics in Medicine.
  5. Ang, B.H., Ho, W.K.,, et. al 2022 Predicting the Likelihood of Carrying a BRCA1 or BRCA2 Mutation in Asian Patients With Breast Cancer. Journal of Clinical Oncology
  6. Ho, W.K., et. al 2020 European polygenic risk score for prediction of breast cancer shows similar performance in Asian women. Nature Communications.
  7. Mariapun, S., Ho, W. K., et. al 2016 Variants in 6q25.1 are associated with mammographic density in Malaysian Chinese women. CEBP