Dr Ang Mia Yang
- Senior Lecturer
- Jeffrey Cheah 红杏视频 Medical School
Biography
Dr Ang Mia Yang is a researcher and educator specializing in clinical bioinformatics. His academic trajectory has been supported by competitive government funding, notably the MEXT Scholarship from the Japanese government for his doctoral training at The University of Tokyo, and a JPA scholarship for his local studies in Malaysia.
His research focuses on the transition toward data-driven precision medicine by integrating multi-omics data with machine learning to identify specific genetic and environmental markers of health. Through various research collaborations, he performs advanced bioinformatics analyses to map complex biological landscapes, such as the genetic drivers of obesity to pinpoint potential causal genes and therapeutic targets.
Another core component of his expertise lies in microbial genomics and the development of specialized bioinformatic tools designed to facilitate research. He co-developed the AMRColab platform, a tool for antimicrobial resistance surveillance supported by the Bill & Melinda Gates Foundation via PHA4GE. He also co-developed several tools for microbial genome analysis, including FusoBase and MycoBase, which provide the scientific community with accessible infrastructure for comparative genomics.
His technical background is further supported by experience in managing High-Performance Computing (HPC) environments and building reproducible bioinformatic pipelines. Dr Yang's professional work spans academia, government-linked scientific initiatives, and industry. He is an Affiliate Member of the Young Scientist Network - Academy of Sciences Malaysia (YSN-ASM) and serves as a Key Opinion Leader (KOL) in Bioinformatics, AI, and Machine Learning for the private sector.
His professional footprint includes ongoing international collaborations, particularly with partners in Japan, China, Indonesia, the Philippines, and the UAE. In his teaching role, Dr Yang utilizes hands-on, project-based learning to prepare the next generation of biomedical scientists. His approach emphasizes the practical application of industry-standard computational tools and the development of systematic analytical frameworks, ensuring that students are prepared to navigate the evolving demands of the global life sciences landscape.
Academic & Professional Qualifications
- Bachelor of Science (Hons) in Bioinformatics, The National University of Malaysia, Malaysia (2012)
- Master of Dental Science (MDSc), University of Malaya, Malaysia (2015)
- Doctor of Philosophy (Ph.D.) in Medical Science, The University of Tokyo, Japan (2024)
Research Interests
- Integrative Multi-Omics & Systems Biology
- Clinical Bioinformatics & Precision Medicine
- Pathogen Functional Genomics & Virulence Modeling
- Computational Drug Discovery & Biomarker Identification
- Data Driven Biomedical Data Science
Teaching Areas
- Precision Medicine & Multi-Omics
- Computational Systems Biology
- Biomedical Data Science
- Next-Generation Sequencing Analysis
- Advanced Bioinformatics Programming
Notable Publications
- Ang, M. Y., et al. (2025). "Misidentification of Staphylococcus epidermidis M15_2005 in a diagnostic microbiology laboratory: Whole genome sequencing as a confirmatory tool?" Malays. J. Microbiol.
- Chen, L., et al. (2025). 鈥淪quama Manitis Extract Exhibits Broad-Spectrum Antibacterial Activity Through Energy and DNA Disruption Mechanisms鈥. Biology.
- Lam, S. D., et al. (2024). "AMRColab - a user-friendly antimicrobial resistance detection and visualization tool." Microb. Genom.
- Farook, N. A. M., et al. (2024). "Desiccation tolerance and reduced antibiotic resistance: Key drivers in ST239-III to ST22-IV MRSA clonal replacement at a Malaysian teaching hospital." Int. J. Med. Microbiol.
- Ang, M. Y., et al. (2022). "Draft Genome Sequences of Four Methicillin-Resistant Staphylococcus aureus Strains (M080_2017, M106_2017, M181_2017, and M191_2017), Isolated from a Malaysian Teaching Hospital." Microbiol. Resour. Announc.
- Farook, N. A. M., et al. (2022). "Diversity and Dissemination of Methicillin-Resistant Staphylococcus aureus (MRSA) Genotypes in Southeast Asia." Trop. Med. Infect. Dis.
- Osman, M. A., et al. (2021). "Parvimonas micra, Peptostreptococcus stomatis, Fusobacterium nucleatum and Akkermansia muciniphila as a four-bacteria biomarker panel of colorectal cancer." Sci. Rep.
- Choo, S. W., et al. (2016). "Comparative Genomic Analysis Reveals a Possible Novel Non-Tuberculous Mycobacterium Species with High Pathogenic Potential." PLoS One.
- Ang, M. Y., et al. (2016). "Comparative Genome Analysis of Fusobacterium nucleatum." Genome Biol. Evol.
- Ang, M. Y., et al. (2014). "Genome Sequence of Fusobacterium nucleatum Strain W1481, a Possible New Subspecies Isolated from a Periodontal Pocket." Genome Announc.
- Ang, M. Y., et al. (2013). "Genome Sequence of Parvimonas micra Strain A293, Isolated from an Abdominal Abscess from a Patient in the United Kingdom." Genome Announc.
- Tan, J. L., et al. (2013). "First Whole-Genome Sequence of Mycobacterium iranicum, a Newly Reported Mycobacterial Species." Genome Announc.
- Ang, M. Y., et al. (2023). "Deciphering the genetic landscape of obesity: a data-driven approach to identifying plausible causal genes and therapeutic targets." J. Hum. Genet.
- Takeuchi, F., et al. (2023). "Gene-regulation modules in nonalcoholic fatty liver disease revealed by single-nucleus ATAC-seq." Life Sci. Alliance.
- Takeuchi, F., et al. (2022). "Transcriptomic Response in the Heart and Kidney to Different Types of Antihypertensive Drug Administration." Hypertension.
- Ang, M. Y., et al. (2019). "Proteogenomics: From next-generation sequencing (NGS) and mass spectrometry-based proteomics to precision medicine." Clin. Chim. Acta.
- Low, T. Y., et al. (2019). "Connecting Proteomics to Next-Generation Sequencing: Proteogenomics and Its Current Applications in Biology." Proteomics.
- Zheng, W., et al. (2016). "NeisseriaBase: a specialised Neisseria genomic resource and analysis platform." PeerJ.
- Choo, S. W., et al. (2015). "MycoCAP - Mycobacterium Comparative Analysis Platform." Sci. Rep.
- Tan, S. Y., et al. (2015). "YersiniaBase: a genomic resource and analysis platform for comparative analysis of Yersinia." BMC Bioinformatics.
- Tan, M. F., et al. (2015). "Development of ListeriaBase and comparative analysis of Listeria monocytogenes." BMC Genomics.
- Ang, M. Y., et al. (2014). "FusoBase: an online Fusobacterium comparative genomic analysis platform." Database (Oxford).
- Aljarousha, M., et al. (2025). "Depression, anxiety, stress, and dry eye disease among Gazan undergraduate health sciences and nursing students: a structural equation modeling study." Cont. Lens Anterior Eye.
- Choo, S. W., et al. (2022). "A collective statement in support of saving pangolins." Sci. Total Environ.
Achievements & Accolades
Research Grants
International
Co-Investigator, PHA4GE Anti-microbial Resistance (AMR) Sub-Grant, Bill & Melinda Gates Foundation (via PHA4GE) | 2021 鈥 2022 | USD 20,000
National
Principal Investigator, MSU Industrial Collaboration Grant (MICG), Management and Science University | 2025 鈥 2027 | RM 20,000
Fellowships and Scholarships
International
Japanese Government (MEXT) Postgraduate Scholarship, Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan | 2020 鈥 2024
National
High Impact Research (HIR) Graduate Research Assistant Scheme (GRAS), Ministry of Higher Education (MOHE) / University of Malaya | 2013 鈥 2015
National Public Service Department (JPA) Scholarship, Jabatan Perkhidmatan Awam (JPA), Malaysia | 2009 鈥 2012
Professional Associations
- American Society for Microbiology (ASM) | U.S.
- International Society for Computational Biology (ISCB) | U.S.
- Japan Society of Human Genetics (JSHG) | Japan
- Malaysian Society of Bioinformatics and Computational Biology (MaSBiC) | Malaysia
- Young Scientist Network 鈥 Academy of Sciences Malaysia (YSN 鈥 ASM) | Malaysia